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The gut–brain axis is the two-way communication system between your gastrointestinal tract and your brain. This connection involves multiple pathways, including the nervous system (especially the vagus nerve), the immune system, and circulating metabolites and hormones produced in the gut.
The gut–brain connection means that signals don’t just go from the brain to control digestion—your gut also sends information back that can influence mood, cognition, and overall neurological function. A key player in this process is the gut microbiome, which produces molecules (like short-chain fatty acids, neurotransmitter precursors, and metabolites) that interact with both local gut cells and distant organs, including the brain.
In simple terms, the gut and brain are in constant dialogue, and changes in gut health can affect how the brain functions, just as stress and brain activity can affect the gut.
Stella Maris Therapeutics, LLC
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